About Us

While most subjects enter clinical trials for the right reasons, a statistically powerful number of subjects have found that they can participate in several studies at once. Their motivations may be to increase the chances of receiving active medication, or to receive attention from health care professionals. However, by far the most common motivation is financial gain. Professional subjects may tell investigators what they need to hear in order to be enrolled, collect multiple stipends and not take study medications, while reporting perfect adherence. The professional subject problem is particularly acute in studies with subjective endpoints, such as in psychiatry or pain. Before subject registries existed, duplicate subjects were tracked internally within a few pharmaceutical companies. This only detected the tip of the iceberg, as participation across sponsors or indications was not tracked. Professional subjects may magnify symptoms to meet ratings criteria, only to improve dramatically and skew study results. Professional subjects who do not take study medication or placebo may influence study results. Even those who do take study medication may deny exclusionary conditions and previous study participation, threatening their safety. Websites are available to assist and support subject participation in multiple studies, such as GPGP (guinea pig guinea pig).net, JALR (Just Another Lab Rat).org and Study Scavenger. For more information, please contact us at support@subjectregistry.com